November 2015
Upasana Ray > Other Awards
This award is given by Science and Engineering Research Board (SERB) to post-doctoral fellows from all over the world to take up scientific positions in India. I was awarded this fellowship to carry out independent research on Dengue virus pathogenesis and to design virus like particle based vaccine for Dengue infection.
July 2015
Upasana Ray > Other Awards
This award was given by the Indian National Science Academy as a recognition for my work done in India
September 2014
Upasana Ray > Other Awards
The award was given by the 'Center for Cancer Research', National Institutes of Health for deisigning virus like particle based vaccine for JC polyomavirus based Progressive Multifocal Leukoencephalopathy (PML) and for proposing a neutralization assay based screening strategy for PML at-risk individuals.
September 2013
Upasana Ray > Other Awards
This award was given by National Institutes of Health for a part of my research work as a contribution of a post-doctoral fellow
April 2012
Upasana Ray > Other Awards
This is a fellowship for persuing post-doctoral fellowship at National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States
February 2010
Upasana Ray > Other Awards
This award was given for the International Centre of Genetic Engineering and Biotechnology (ICGEB)-IUBMB workshop on ‘Human RNA Viruses’ held in New Delhi, India
May 2009
Upasana Ray > Other Awards
The best poster award was presented at the IISc Centenary Symposium on Biology and Pathogenesis of viruses: Molecular Insights at Indian Institute of Science, Bangalore, Karnataka, India
September 2010
Upasana Ray > Other Awards
Given by the 'Council of Scientific and Industrial Research', India
December 2006
Upasana Ray > Other Awards
Given by the 'Council of Scientific and Industrial Research', India
Awards
Degrees:
2012
Doctorate
Structural, Cell and Molecular Biology
Publications resulting from Research
1. Ray, U. 2016. Virus like nanoparticles: Display matters Proceedings of Indian National Science Academy (Accepted) (Review)
2. Ray, U., Cinque, P., Gerevini, S., Longo, V., Lazzarin, A., Schippling, S., Martin, R., Buck, C.B., and Pastrana, D.V. 2015. JC polyomavirus mutants escape antibody-mediated neutralization. Science Translational Medicine. 7(306):306ra151(PMID:26400912)
3. Ray, U., Roy, C. L., Kumar, A. , Mani, P., Joseph, A. P., Sudha, G., Sarkar, D. P., Srinivasan, N., and Das, S. 2013. Inhibition of the interaction between NS3 protease and HCV IRES with a small peptide: A novel therapeutic strategy. Molecular Therapy (Nature Publishing Group). 21(1):57-67. (PMID:22910295)
4. Ray, U., Ray, P. S. and Das, S. 2012 Ribosome-RNA interaction: A potential target for developing antiviral against hepatitis C virus. Current Science. Vol 102; No. 3. (Review)
5. Ray, U., and Das, S. 2011. Interplay between NS3 protease and human La protein regulates translation-replication switch of Hepatitis C virus. Scientific Reports (Nature Publishing Group) 1:1. (PMID:22355520)
6. *Mondal, T., *Ray, U., Manna, A. K., Gupta, R., Roy, S., and Das, S. 2008. Structural determinant of human La protein critical for internal initiation of translation of hepatitis C virus RNA. Journal of Virology 82:11927-38. (*joint first authors) (PMCID:18829760) (Cover page article)
Second Author
7. Kumar, A., Manna, A. K., Ray, U., Mullick, R., Basu, G., Das, S. and Roy, S. 2014.Specific sequence of a beta-turn in human La protein may contribute to species specificity of Hepatitis C virus. Journal of Virology 88(8):4319-27 (PMID:24478427)
8. Pastrana, D. V., Ray, U., Magaldi, T. G., Schowalter, R., M., Cuburu, N., and Buck, C. B. 2013. BK polyomavirus genotypes represent distinct serotypes with distinct entry tropism. Journal of Virology 87(18):10105-13 (PMID:23843634)
9. Kumar, A., Ray, U. and Das, S. 2013. Human La protein Interaction with GCAC near the initiator AUG enhances HCV RNA replication by Promoting Linkage Between 5'-and 3'- untranslated regions. Journal of Virology 87(12):6713-26 (PMID:23552417)
10. Manna, A. K., Kumar, A., Ray, U., Das, S., Basu, G. and Roy, S. 2013. A cyclic peptide mimic of an RNA recognition motif of human La protein is a potent inhibitor of hepatitis C virus. Antiviral Research 97(3):223-226. (PMID:23291201)
11. Ravikumar, Y. S., Ray, U., Nandhitha, M., Perween, A., Raja Naika, H., Khanna, N. and Das, S. 2011. Inhibition of hepatitis C virus replication by herbal extract: Phyllanthus amarus as potent natural source. Virus Research 158:89-97. (PMID:21440018)
Patents
1. Treating or Inhibiting JC polyomavirus infection and JC polyomavirus-associated progressive multifocal leukoencephalopathy. Christopher Buck, Upasana Ray, Diana Pastrana (US Application number: 61/919,043)
2. Compositions, method and formulations for peptide based inhibitors of Hepatitis C virus replication. Saumitra Das, Upasana Ray, Debi P. Sarkar, Chaitrali Laha Roy, N. Srinivasan. (Application number: 4033/CHE/2011 A)
3. Small antiviral peptides against Hepatitis C virus. Saumitra Das, Siddhartha Roy, Upasana Ray, Tanmoy Mondal, Asit Kumar Manna, Romi Gupta. (US Application number: 2009/0233868A1)
Book Chapters
1. Upasana Ray, Saumitra Das (2009) Role of Human La protein in Translation and Replication of Hepatitis C Virus. Mechanisms of Microbial Pathogenesis. TATA McGraw-Hill publication.
2. Upasana Ray, Chaitrali Laha Roy, Saumitra Das (2011) Viruses and our fight against them. UGC-sponsored national seminar on microbiology: development and challenges in basic and applied research (organized by department of microbiology, Ramakrishna Mission Vidyamandira, Belur Math in collaboration with Bose Institute, Kolkata)
Research Highlight/ Coverage
1. Therapeutic opportunity knocks (2015): Science (Vol. 349; Issue: 6255; page-1501)
2. Studies propose vaccination for troublemaking virus (2015): Multiple Sclerosis Discovery Forum
3. Closing “blind spots” in patients’ immune response to lethal brain infection (2015): EurekaAlert
4. Researchers work towards vaccination for PML (2015): MS UN Master Cylinder (Breaking News)
5. Possible JC virus vaccination offers important implications for MS treatment (2015): Multiple Sclerosis News Today
6. Hep C viral switch (2011): Nature India (doi:10.1038/nindia.2011.83)
2. Ray, U., Cinque, P., Gerevini, S., Longo, V., Lazzarin, A., Schippling, S., Martin, R., Buck, C.B., and Pastrana, D.V. 2015. JC polyomavirus mutants escape antibody-mediated neutralization. Science Translational Medicine. 7(306):306ra151(PMID:26400912)
3. Ray, U., Roy, C. L., Kumar, A. , Mani, P., Joseph, A. P., Sudha, G., Sarkar, D. P., Srinivasan, N., and Das, S. 2013. Inhibition of the interaction between NS3 protease and HCV IRES with a small peptide: A novel therapeutic strategy. Molecular Therapy (Nature Publishing Group). 21(1):57-67. (PMID:22910295)
4. Ray, U., Ray, P. S. and Das, S. 2012 Ribosome-RNA interaction: A potential target for developing antiviral against hepatitis C virus. Current Science. Vol 102; No. 3. (Review)
5. Ray, U., and Das, S. 2011. Interplay between NS3 protease and human La protein regulates translation-replication switch of Hepatitis C virus. Scientific Reports (Nature Publishing Group) 1:1. (PMID:22355520)
6. *Mondal, T., *Ray, U., Manna, A. K., Gupta, R., Roy, S., and Das, S. 2008. Structural determinant of human La protein critical for internal initiation of translation of hepatitis C virus RNA. Journal of Virology 82:11927-38. (*joint first authors) (PMCID:18829760) (Cover page article)
Second Author
7. Kumar, A., Manna, A. K., Ray, U., Mullick, R., Basu, G., Das, S. and Roy, S. 2014.Specific sequence of a beta-turn in human La protein may contribute to species specificity of Hepatitis C virus. Journal of Virology 88(8):4319-27 (PMID:24478427)
8. Pastrana, D. V., Ray, U., Magaldi, T. G., Schowalter, R., M., Cuburu, N., and Buck, C. B. 2013. BK polyomavirus genotypes represent distinct serotypes with distinct entry tropism. Journal of Virology 87(18):10105-13 (PMID:23843634)
9. Kumar, A., Ray, U. and Das, S. 2013. Human La protein Interaction with GCAC near the initiator AUG enhances HCV RNA replication by Promoting Linkage Between 5'-and 3'- untranslated regions. Journal of Virology 87(12):6713-26 (PMID:23552417)
10. Manna, A. K., Kumar, A., Ray, U., Das, S., Basu, G. and Roy, S. 2013. A cyclic peptide mimic of an RNA recognition motif of human La protein is a potent inhibitor of hepatitis C virus. Antiviral Research 97(3):223-226. (PMID:23291201)
11. Ravikumar, Y. S., Ray, U., Nandhitha, M., Perween, A., Raja Naika, H., Khanna, N. and Das, S. 2011. Inhibition of hepatitis C virus replication by herbal extract: Phyllanthus amarus as potent natural source. Virus Research 158:89-97. (PMID:21440018)
Patents
1. Treating or Inhibiting JC polyomavirus infection and JC polyomavirus-associated progressive multifocal leukoencephalopathy. Christopher Buck, Upasana Ray, Diana Pastrana (US Application number: 61/919,043)
2. Compositions, method and formulations for peptide based inhibitors of Hepatitis C virus replication. Saumitra Das, Upasana Ray, Debi P. Sarkar, Chaitrali Laha Roy, N. Srinivasan. (Application number: 4033/CHE/2011 A)
3. Small antiviral peptides against Hepatitis C virus. Saumitra Das, Siddhartha Roy, Upasana Ray, Tanmoy Mondal, Asit Kumar Manna, Romi Gupta. (US Application number: 2009/0233868A1)
Book Chapters
1. Upasana Ray, Saumitra Das (2009) Role of Human La protein in Translation and Replication of Hepatitis C Virus. Mechanisms of Microbial Pathogenesis. TATA McGraw-Hill publication.
2. Upasana Ray, Chaitrali Laha Roy, Saumitra Das (2011) Viruses and our fight against them. UGC-sponsored national seminar on microbiology: development and challenges in basic and applied research (organized by department of microbiology, Ramakrishna Mission Vidyamandira, Belur Math in collaboration with Bose Institute, Kolkata)
Research Highlight/ Coverage
1. Therapeutic opportunity knocks (2015): Science (Vol. 349; Issue: 6255; page-1501)
2. Studies propose vaccination for troublemaking virus (2015): Multiple Sclerosis Discovery Forum
3. Closing “blind spots” in patients’ immune response to lethal brain infection (2015): EurekaAlert
4. Researchers work towards vaccination for PML (2015): MS UN Master Cylinder (Breaking News)
5. Possible JC virus vaccination offers important implications for MS treatment (2015): Multiple Sclerosis News Today
6. Hep C viral switch (2011): Nature India (doi:10.1038/nindia.2011.83)
DNA tumor virus meeting
2025
Neurovirulent JC polyomavirus mutants escape antibody mediated neutralization
American Society for Virology (ASV) meeting
2025
JC polyomavirus antibody-escape mutants in progressive multifocal leukoencephalopathy
DNA tumor virus meeting
2025
Antibody-Mediated neutralization of neurovirulent JC polyomaviruses
HIV/AIDS and cancer virology fall Think-Tank meeting
2025
Antibody-Mediated immunity against JC polyomaviruses causing progressive multifocal leukoencephalopathy
HIV/AIDS and cancer virology fall Think-Tank meeting
2025
Antibody-Mediated neutralization of neurovirulent JC polyomaviruses
Indo-Singapore meeting
2025
The translation replication switch in HCV
2nd Virology meeting
2025
Targeting NS3 protease-HCV RNA interaction: A novel antiviral target
RNA 2010
2025
Translation Replication switch of Hepatitis C Virus RNA
ICGEB-IUBMB workshop ‘Human RNA Viruses’
2025
Determinant within NS3 protease critical for RNA binding to mediate the switch from translation to replication of Hepatitis C Viral RNA
79th Annual Meeting of the Society of Biological Chemists (Theme: Regulation of biochemical and cellular processes in diverse systems)
2025
Interplay between NS3 protease and human La protein regulates translation to replication in hepatitis C virus
IISc centenary symposium on biology and pathogenesis of viruses: Molecular insights
2025
The interplay between NS3 protease and human La protein: Switch of translation to replication
IISc Centenary Symposium on ‘Mechanisms of microbial pathogenesis’
2025
HCV NS3 protease interacts with HCV 5’UTR: Implications on multifunctional activities
15th international symposium on Hepatitis C Virus and related viruses
2025
Specific interaction of the protease domain of the NS3 protein with the HCV 5’UTR: possible implications
77th Annual Meeting of the Society of Biological Chemists (Theme: impact of basic and translational research on medicine, agriculture and industry)
2025
The protease domain of Hepatitis C virus NS3 protein interacts with the 5’UTR: Implications on multifunctional activity
Guest lecture
2025
Virus-Host Interaction: Disease and Remedy
Guest lecture
2025
Virus-Host Interaction
DNA tumor virus meeting
2025
American Society for Virology (ASV) meeting
2025
DNA tumor virus meeting
2025
HIV/AIDS and cancer virology fall Think-Tank meeting
2025
HIV/AIDS and cancer virology fall Think-Tank meeting
2025
Indo-Singapore meeting
2025
2nd Virology meeting
2025
RNA 2010
2025
ICGEB-IUBMB workshop ‘Human RNA Viruses’
2025
79th Annual Meeting of the Society of Biological Chemists
2025
IISc centenary symposium on biology and pathogenesis of viruses: Molecular insights
2025
IISc Centenary Symposium on ‘Mechanisms of microbial pathogenesis’
2025
15th international symposium on Hepatitis C Virus and related viruses
2025
77th Annual Meeting of the Society of Biological Chemists
2025
DNA Tumor virus meeting
2025