OWSD PhD Fellowship
OWSD Early Career
2023
Moura Mendes Arrua Juliana
About the project
Her research project will develop new antifungal agents and combinations that can effectively combat emerging and neglected fungal pathogens. Fungal infections are an understudied global public health concern. Treatment options are limited and in many settings are expensive and toxic. In addition, the rapid emergence of resistance to antifungal drugs in recent years is an emerging health threat. This study will characterize the fungi considered priority according to WHO - Aspergillus, Fusarium, and Sporothrix - and evaluate the antifungal effect of natural products and synthetic compounds and their possible mechanisms of action, including changes in the proteome of the fungal isolates susceptible to the drug under study. The results generated will constitute a basis for the design of new antifungal treatment strategies, with special attention to sporotrichosis.
Field of Specialization
Position
Researcher
About the institution
Universidad Nacional de Asunción
Centro Multidisciplinario de Investigaciones Tecnológicas - CEMIT
Full Member
Dr. Juliana Moura Mendes Arrua
Membership since:
2022
Field of activity:
Other Memberships/Affiliations
Federación Latinoamericana de Colecciones de Cultivos - FELACC
Red Iberoamericana de Investigadores en Micología - RIIMICO
Sociedad Paraguaya de Microbiología - SPM
Degrees:
2021
Doctorate
Medical and Health Sciences incl Neurosciences
2012
Master
Medical and Health Sciences incl Neurosciences
2008
Undergraduate
Medical and Health Sciences incl Neurosciences
Publications resulting from Research
- Antifungal activity of geraniol and citronellol, two monoterpenes alcohols, against Trichophyton rubrum involves inhibition of ergosterol biosynthesis. 2015. FO Pereira, JM Mendes, IO Lima, KSL Mota, WA Oliveira, EO Lima. Pharmaceutical biology 53 (2), 228-234. DOI: 10.3109/13880209.2014.913299
- Actividad antifúngica del aceite esencial de Eugenia caryophyllata sobre cepas de Candida tropicalis de aislados clínicos. 2012.
JM Mendes, FQS Guerra, F de Oliveira Pereira, JP de SOUSA...Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas. 11 (3): 208 - 217.
- Presencia de aflatoxina M1 en fórmulas lácteas infantiles comercializadas en el área metropolitana a Asunción, Paraguay. 2021.
AA Arrúa, PD Arrua, MGU Mayans, MYQ Viay, JM Lara, JM Mendes. Pediatría (Asunción). DOI: https://doi.org/10.31698/ped.48012021007
- Presence of Aflatoxin M1 in Commercial Milk in Paraguay AA Arrua, PD Arrúa, J Moura-Mendes, C Cazal, FP Ferreira, ...
Journal of Food Protection 84 (12), 2128-2132. https://doi.org/10.4315/JFP-21-196.
- Evaluating the Antifungal Activity of α-Bisabolol in Association with NaCl on Fusarium oxysporum in Maize Grains CAC de Medeiros, ÂV Pinto, JC de Oliveira, GS Silva, JMM Arrua, IO Lima, ...2021. Current Microbiology 78 (2), 604-610. https://doi.org/10.1007/s00284-020-02313-8.
- Prevalence of Candida tropicalis and Candida krusei in onychomycosis in João Pessoa, Paraiba, Brazil from 1999 to 2010. 2015. JMM Arrua, LAS Rodrigues, FO Pereira, EO Lima. Anais da Academia Brasileira de Ciências 87, 1819-1822. http://dx.doi.org/10.1590/0001-3765201520130418.
- Evaluación preliminar del efecto antimicrobiano y toxicidad aguda del extracto etanólico bruto de Luehea divaricata (Ka’a ovetĩ)
JMM Arrúa, G Franco, PA Ibarra, TRL Arias. Investigaciones y Estudios-UNA 11 (2), 78-86
- Evaluation of wheat genotypes resistance to Fusarium head blight in Paraguay. 2020. CC Cazal-Martínez, YM Reyes-Caballero, PE Pérez-Estigarribia, ...Pesquisa Agropecuária Tropical. v. 50, e63609. DOI: 10.1590/1983-40632020v5063609.
- Occurrence of deoxynivalenol and ochratoxin A in beers and wines commercialized in Paraguay. 2019. AA Arrúa, JM Mendes, P Arrúa, FP Ferreira, G Caballero, C Cazal, ...Toxins. 11 (6), 308; doi:10.3390/toxins11060308
- Patent application: Patent of Invention (PI) - BR 10 2018 074391 0: Antifungal composition for phytopathogenic disease control phytopathogenic diseases composed of mixtures of Alpha-bisabolol and NaCl.
- Actividad antifúngica del aceite esencial de Eugenia caryophyllata sobre cepas de Candida tropicalis de aislados clínicos. 2012.
JM Mendes, FQS Guerra, F de Oliveira Pereira, JP de SOUSA...Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas. 11 (3): 208 - 217.
- Presencia de aflatoxina M1 en fórmulas lácteas infantiles comercializadas en el área metropolitana a Asunción, Paraguay. 2021.
AA Arrúa, PD Arrua, MGU Mayans, MYQ Viay, JM Lara, JM Mendes. Pediatría (Asunción). DOI: https://doi.org/10.31698/ped.48012021007
- Presence of Aflatoxin M1 in Commercial Milk in Paraguay AA Arrua, PD Arrúa, J Moura-Mendes, C Cazal, FP Ferreira, ...
Journal of Food Protection 84 (12), 2128-2132. https://doi.org/10.4315/JFP-21-196.
- Evaluating the Antifungal Activity of α-Bisabolol in Association with NaCl on Fusarium oxysporum in Maize Grains CAC de Medeiros, ÂV Pinto, JC de Oliveira, GS Silva, JMM Arrua, IO Lima, ...2021. Current Microbiology 78 (2), 604-610. https://doi.org/10.1007/s00284-020-02313-8.
- Prevalence of Candida tropicalis and Candida krusei in onychomycosis in João Pessoa, Paraiba, Brazil from 1999 to 2010. 2015. JMM Arrua, LAS Rodrigues, FO Pereira, EO Lima. Anais da Academia Brasileira de Ciências 87, 1819-1822. http://dx.doi.org/10.1590/0001-3765201520130418.
- Evaluación preliminar del efecto antimicrobiano y toxicidad aguda del extracto etanólico bruto de Luehea divaricata (Ka’a ovetĩ)
JMM Arrúa, G Franco, PA Ibarra, TRL Arias. Investigaciones y Estudios-UNA 11 (2), 78-86
- Evaluation of wheat genotypes resistance to Fusarium head blight in Paraguay. 2020. CC Cazal-Martínez, YM Reyes-Caballero, PE Pérez-Estigarribia, ...Pesquisa Agropecuária Tropical. v. 50, e63609. DOI: 10.1590/1983-40632020v5063609.
- Occurrence of deoxynivalenol and ochratoxin A in beers and wines commercialized in Paraguay. 2019. AA Arrúa, JM Mendes, P Arrúa, FP Ferreira, G Caballero, C Cazal, ...Toxins. 11 (6), 308; doi:10.3390/toxins11060308
- Patent application: Patent of Invention (PI) - BR 10 2018 074391 0: Antifungal composition for phytopathogenic disease control phytopathogenic diseases composed of mixtures of Alpha-bisabolol and NaCl.